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Senkyunolide A inhibits the progression of osteoarthritis by inhibiting the NLRP3 signalling pathway

CONTEXT: Osteoarthritis (OA) is a degenerative disease. Senkyunolide A (SenA) is an important phthalide from Ligusticum chuanxiong Hort (Umbelliferae) with anti-spasmodic and neuroprotective effects. OBJECTIVE: We explored the effect of SenA on IL-1β-stimulated chondrocytes and OA mice MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Shao, Minglei, Lv, Dongwei, Zhou, Kai, Sun, Haijun, Wang, Zhitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890578/
https://www.ncbi.nlm.nih.gov/pubmed/35225151
http://dx.doi.org/10.1080/13880209.2022.2042327