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Cell-penetrating peptides containing the progesterone receptor polyproline domain inhibits EGF signaling and cell proliferation in lung cancer cells

Non-small cell lung cancer (NSCLC) accounts for the majority (80–85%) of all lung cancers. All current available treatments have limited efficacy. The epidermal growth factor receptor (EGFR) plays a critical role in the development and progression of NSCLC, with high EGFR expression associated with...

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Detalles Bibliográficos
Autores principales: Kaewjanthong, Panthita, Sooksai, Sarintip, Sasano, Hironobu, Hutvagner, Gyorgy, Bajan, Sarah, McGowan, Eileen, Boonyaratanakornkit, Viroj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890653/
https://www.ncbi.nlm.nih.gov/pubmed/35235599
http://dx.doi.org/10.1371/journal.pone.0264717