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PAI-1 is a vascular cell–specific HIF-2–dependent angiogenic factor that promotes retinal neovascularization in diabetic patients

For patients with proliferative diabetic retinopathy (PDR) who do not respond adequately to pan-retinal laser photocoagulation (PRP) or anti–vascular endothelial growth factor (VEGF) therapies, we hypothesized that vascular cells within neovascular tissue secrete autocrine/paracrine angiogenic facto...

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Detalles Bibliográficos
Autores principales: Qin, Yaowu, Zhang, Jing, Babapoor-Farrokhran, Savalan, Applewhite, Brooks, Deshpande, Monika, Megarity, Haley, Flores-Bellver, Miguel, Aparicio-Domingo, Silvia, Ma, Tao, Rui, Yuan, Tzeng, Stephany Y., Green, Jordan J., Canto-Soler, M. Valeria, Montaner, Silvia, Sodhi, Akrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890718/
https://www.ncbi.nlm.nih.gov/pubmed/35235351
http://dx.doi.org/10.1126/sciadv.abm1896