Chimerism through the activation of invariant natural killer T cells prolongs graft survival after transplantation of induced pluripotent stem cell–derived allogeneic cardiomyocytes

The loss of functional cells through immunological rejection after transplantation reduces the efficacy of regenerative therapies for cardiac failure that use allogeneic induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). Recently, mixed-chimera mice with donor-specific immunotolerance...

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Detalles Bibliográficos
Autores principales: Yoshida, Shohei, Miyagawa, Shigeru, Matsuzaki, Takashi, Ishii, Yasuyuki, Fukuda-Kawaguchi, Emi, Kawamura, Takuji, Kawamura, Ai, Nakamura, Yuki, Toda, Koichi, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890721/
https://www.ncbi.nlm.nih.gov/pubmed/35235568
http://dx.doi.org/10.1371/journal.pone.0264317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890721/
https://www.ncbi.nlm.nih.gov/pubmed/35235568
http://dx.doi.org/10.1371/journal.pone.0264317

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