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eNAMPT actions through nucleus accumbens NAD(+)/SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress

Obesity is frequently associated with impairments in the social domain, and stress at puberty can lead to long-lasting changes in visceral fat deposition and in social behaviors. However, whether stress-induced changes in adipose tissue can affect fat-to-brain signaling, thereby orchestrating behavi...

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Detalles Bibliográficos
Autores principales: Morató, Laia, Astori, Simone, Zalachoras, Ioannis, Rodrigues, Joao, Ghosal, Sriparna, Huang, Wei, Guillot de Suduiraut, Isabelle, Grosse, Jocelyn, Zanoletti, Olivia, Cao, Lei, Auwerx, Johan, Sandi, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890725/
https://www.ncbi.nlm.nih.gov/pubmed/35235362
http://dx.doi.org/10.1126/sciadv.abj9109