Effects of cytochrome P450 2B6 and constitutive androstane receptor genetic variation on Efavirenz plasma concentrations among HIV patients in Kenya

The effects of genetic variation of cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) on efavirenz (EFV) plasma concentration was evaluated among 312 HIV patients in Nairobi Kenya. The EFV plasma concentration at steady-state were determined using ultra-high-performance liquid...

Descripción completa

Detalles Bibliográficos
Autores principales: Ngayo, Musa Otieno, Oluka, Margaret, Kwena, Zachari Arochi, Bulimo, Wallace Dimbuson, Okalebo, Faith Apolot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890732/
https://www.ncbi.nlm.nih.gov/pubmed/35235559
http://dx.doi.org/10.1371/journal.pone.0260872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890732/
https://www.ncbi.nlm.nih.gov/pubmed/35235559
http://dx.doi.org/10.1371/journal.pone.0260872

Ejemplares similares