Grxcr1 regulates hair bundle morphogenesis and is required for normal mechanoelectrical transduction in mouse cochlear hair cells

Tasmanian devil (tde) mice are deaf and exhibit circling behaviour. Sensory hair cells of mutants show disorganised hair bundles with abnormally thin stereocilia. The origin of this mutation is the insertion of a transgene which disrupts expression of the Grxcr1 (glutaredoxin cysteine rich 1) gene....

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Detalles Bibliográficos
Autores principales: Lorente-Cánovas, Beatriz, Eckrich, Stephanie, Lewis, Morag A., Johnson, Stuart L., Marcotti, Walter, Steel, Karen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890737/
https://www.ncbi.nlm.nih.gov/pubmed/35235570
http://dx.doi.org/10.1371/journal.pone.0261530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890737/
https://www.ncbi.nlm.nih.gov/pubmed/35235570
http://dx.doi.org/10.1371/journal.pone.0261530

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