Systematically assessing microbiome–disease associations identifies drivers of inconsistency in metagenomic research

Evaluating the relationship between the human gut microbiome and disease requires computing reliable statistical associations. Here, using millions of different association modeling strategies, we evaluated the consistency—or robustness—of microbiome-based disease indicators for 6 prevalent and well...

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Detalles Bibliográficos
Autores principales: Tierney, Braden T., Tan, Yingxuan, Yang, Zhen, Shui, Bing, Walker, Michaela J., Kent, Benjamin M., Kostic, Aleksandar D., Patel, Chirag J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Meta-Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890741/
https://www.ncbi.nlm.nih.gov/pubmed/35235560
http://dx.doi.org/10.1371/journal.pbio.3001556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890741/
https://www.ncbi.nlm.nih.gov/pubmed/35235560
http://dx.doi.org/10.1371/journal.pbio.3001556

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