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Systematically assessing microbiome–disease associations identifies drivers of inconsistency in metagenomic research
Evaluating the relationship between the human gut microbiome and disease requires computing reliable statistical associations. Here, using millions of different association modeling strategies, we evaluated the consistency—or robustness—of microbiome-based disease indicators for 6 prevalent and well...
Autores principales: | Tierney, Braden T., Tan, Yingxuan, Yang, Zhen, Shui, Bing, Walker, Michaela J., Kent, Benjamin M., Kostic, Aleksandar D., Patel, Chirag J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890741/ https://www.ncbi.nlm.nih.gov/pubmed/35235560 http://dx.doi.org/10.1371/journal.pbio.3001556 |
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