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Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection

Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea and pseudomembranous colitis in the USA. In addition to these symptoms, patients with CDI can develop severe inflammation and tissue damage, resulting in life-threatening toxic megacolon. CDI is mediated by two larg...

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Detalles Bibliográficos
Autores principales: Peritore-Galve, F. Christopher, Shupe, John A., Cave, Rory J., Childress, Kevin O., Washington, M. Kay, Kuehne, Sarah A., Lacy, D. Borden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890742/
https://www.ncbi.nlm.nih.gov/pubmed/35176123
http://dx.doi.org/10.1371/journal.ppat.1010323