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Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection
Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea and pseudomembranous colitis in the USA. In addition to these symptoms, patients with CDI can develop severe inflammation and tissue damage, resulting in life-threatening toxic megacolon. CDI is mediated by two larg...
Autores principales: | Peritore-Galve, F. Christopher, Shupe, John A., Cave, Rory J., Childress, Kevin O., Washington, M. Kay, Kuehne, Sarah A., Lacy, D. Borden |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890742/ https://www.ncbi.nlm.nih.gov/pubmed/35176123 http://dx.doi.org/10.1371/journal.ppat.1010323 |
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