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Safety Evaluation in Healthy Colombian Volunteers of P2Et Extract Obtained from Caesalpinia spinosa: Design 3+3 Phase I Clinical Trial

The polyphenol-enriched extract called P2Et derived from Caesalpinia spinosa (C. spinosa) had antitumor and immunomodulatory activities reported in breast cancer, leukemia, and melanoma. The aim of this study was to evaluate the safety and maximum tolerated dose of P2Et extract in Colombian healthy...

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Detalles Bibliográficos
Autores principales: Duran, María I, Ballesteros-Ramírez, Ricardo, Tellez, Angélica, Torregrosa, Lilian, Olejua, Peter A, Galvis, Silvia, Urueña, Claudia, Fiorentino, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890855/
https://www.ncbi.nlm.nih.gov/pubmed/35251213
http://dx.doi.org/10.1155/2022/7943001