5-Lipoxygenase Inhibition Protects Retinal Pigment Epithelium from Sodium Iodate-Induced Ferroptosis and Prevents Retinal Degeneration

Excessive reactive oxygen species (ROS) contribute to damage of retinal cells and the development of retinal diseases including age-related macular degeneration (AMD). ROS result in increased metabolites of lipoxygenases (LOXs), which react with ROS to induce lipid peroxidation and may lead to ferro...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Jer, Chang-Chien, Guo-Ping, Lin, Sufan, Hsiao, Yu-Ting, Ke, Mu-Chan, Chen, Alexander, Lin, Tsu-Kung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890867/
https://www.ncbi.nlm.nih.gov/pubmed/35251467
http://dx.doi.org/10.1155/2022/1792894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890867/
https://www.ncbi.nlm.nih.gov/pubmed/35251467
http://dx.doi.org/10.1155/2022/1792894

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