Genetic associations of protein-coding variants in human disease

Genome-wide association studies (GWAS) have identified thousands of genetic variants linked to the risk of human disease. However, GWAS have so far remained largely underpowered in relation to identifying associations in the rare and low-frequency allelic spectrum and have lacked the resolution to t...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Benjamin B., Kurki, Mitja I., Foley, Christopher N., Mechakra, Asma, Chen, Chia-Yen, Marshall, Eric, Wilk, Jemma B., Chahine, Mohamed, Chevalier, Philippe, Christé, Georges, Palotie, Aarno, Daly, Mark J., Runz, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891017/
https://www.ncbi.nlm.nih.gov/pubmed/35197637
http://dx.doi.org/10.1038/s41586-022-04394-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891017/
https://www.ncbi.nlm.nih.gov/pubmed/35197637
http://dx.doi.org/10.1038/s41586-022-04394-w

Ejemplares similares