An Isotopic Labeling Approach Linking Natural Products with Biosynthetic Gene Clusters

Major advances in genome sequencing and large-scale biosynthetic gene cluster (BGC) analysis have prompted an age of natural product discovery driven by genome mining. Still, connecting molecules to their cognate BGCs is a substantial bottleneck for this approach. We have developed a mass spectromet...

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Detalles Bibliográficos
Autores principales: McCaughey, Catherine S., van Santen, Jeffrey A., van der Hooft, Justin J. J., Medema, Marnix H., Linington, Roger G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891042/
https://www.ncbi.nlm.nih.gov/pubmed/34969972
http://dx.doi.org/10.1038/s41589-021-00949-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891042/
https://www.ncbi.nlm.nih.gov/pubmed/34969972
http://dx.doi.org/10.1038/s41589-021-00949-6

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