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An Isotopic Labeling Approach Linking Natural Products with Biosynthetic Gene Clusters
Major advances in genome sequencing and large-scale biosynthetic gene cluster (BGC) analysis have prompted an age of natural product discovery driven by genome mining. Still, connecting molecules to their cognate BGCs is a substantial bottleneck for this approach. We have developed a mass spectromet...
Autores principales: | McCaughey, Catherine S., van Santen, Jeffrey A., van der Hooft, Justin J. J., Medema, Marnix H., Linington, Roger G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891042/ https://www.ncbi.nlm.nih.gov/pubmed/34969972 http://dx.doi.org/10.1038/s41589-021-00949-6 |
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