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Development and characterization of anti-fibrotic natural compound similars with improved effectivity

Cardiac fibroblasts constitute the major cell type of the murine and human heart. Once activated, they contribute to an excessive deposition of extracellular matrix (ECM) leading to cardiac fibrosis and subsequently organ dysfunction. With the exception of the pulmonary drugs, nintedanib and pirfeni...

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Detalles Bibliográficos
Autores principales: Kreutzer, Fabian Philipp, Meinecke, Anna, Mitzka, Saskia, Hunkler, Hannah Jill, Hobuß, Lisa, Abbas, Naisam, Geffers, Robert, Weusthoff, Jan, Xiao, Ke, Jonigk, Danny David, Fiedler, Jan, Thum, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891108/
https://www.ncbi.nlm.nih.gov/pubmed/35235052
http://dx.doi.org/10.1007/s00395-022-00919-6