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Development and characterization of anti-fibrotic natural compound similars with improved effectivity
Cardiac fibroblasts constitute the major cell type of the murine and human heart. Once activated, they contribute to an excessive deposition of extracellular matrix (ECM) leading to cardiac fibrosis and subsequently organ dysfunction. With the exception of the pulmonary drugs, nintedanib and pirfeni...
Autores principales: | Kreutzer, Fabian Philipp, Meinecke, Anna, Mitzka, Saskia, Hunkler, Hannah Jill, Hobuß, Lisa, Abbas, Naisam, Geffers, Robert, Weusthoff, Jan, Xiao, Ke, Jonigk, Danny David, Fiedler, Jan, Thum, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891108/ https://www.ncbi.nlm.nih.gov/pubmed/35235052 http://dx.doi.org/10.1007/s00395-022-00919-6 |
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