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Effects of docosanyl ferulate, a constituent of Withania somnifera, on ethanol- and morphine-elicited conditioned place preference and ERK phosphorylation in the accumbens shell of CD1 mice

BACKGROUND: Docosanyl ferulate (DF) is a behaviourally active GABA(A) receptor complex (GABA(A)R) agonist, recently isolated from the standardized methanolic extract of Withania somnifera Dunal (WSE) root. Previous studies have shown that WSE prevents both ethanol- and morphine-dependent acquisition...

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Detalles Bibliográficos
Autores principales: Maccioni, Riccardo, Serra, Marcello, Marongiu, Jacopo, Cottiglia, Filippo, Maccioni, Elias, Bassareo, Valentina, Morelli, Micaela, Kasture, Sanjay B., Acquas, Elio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891193/
https://www.ncbi.nlm.nih.gov/pubmed/35088095
http://dx.doi.org/10.1007/s00213-022-06069-w