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Effects of docosanyl ferulate, a constituent of Withania somnifera, on ethanol- and morphine-elicited conditioned place preference and ERK phosphorylation in the accumbens shell of CD1 mice
BACKGROUND: Docosanyl ferulate (DF) is a behaviourally active GABA(A) receptor complex (GABA(A)R) agonist, recently isolated from the standardized methanolic extract of Withania somnifera Dunal (WSE) root. Previous studies have shown that WSE prevents both ethanol- and morphine-dependent acquisition...
Autores principales: | Maccioni, Riccardo, Serra, Marcello, Marongiu, Jacopo, Cottiglia, Filippo, Maccioni, Elias, Bassareo, Valentina, Morelli, Micaela, Kasture, Sanjay B., Acquas, Elio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891193/ https://www.ncbi.nlm.nih.gov/pubmed/35088095 http://dx.doi.org/10.1007/s00213-022-06069-w |
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