Pre- and Postnatal Maturation are Important for Fentanyl Exposure in Preterm and Term Newborns: A Pooled Population Pharmacokinetic Study

BACKGROUND AND OBJECTIVE: Fentanyl is an opioid commonly used to prevent and treat severe pain in neonates; however, its use is off label and mostly based on bodyweight. Given the limited pharmacokinetic information across the entire neonatal age range, we characterized the pharmacokinetics of fenta...

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Detalles Bibliográficos
Autores principales: Wu, Yunjiao, Völler, Swantje, Flint, Robert B., Simons, Sinno H. P., Allegaert, Karel, Fellman, Vineta, Knibbe, Catherijne A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891207/
https://www.ncbi.nlm.nih.gov/pubmed/34773609
http://dx.doi.org/10.1007/s40262-021-01076-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891207/
https://www.ncbi.nlm.nih.gov/pubmed/34773609
http://dx.doi.org/10.1007/s40262-021-01076-0

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