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Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia

The neurobiological effects of clozapine are under characterised. We examined the effects clozapine treatment on subcortical volume and cortical thickness and investigated whether macrostructural changes were linked to alterations in glutamate or N-acetylaspartate (NAA). Data were acquired in 24 pat...

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Detalles Bibliográficos
Autores principales: Krajner, Fanni, Hadaya, Laila, McQueen, Grant, Sendt, Kyra-Verena, Gillespie, Amy, Avila, Alessia, Lally, John, Hedges, Emily P., Diederen, Kelly, Howes, Oliver D., Barker, Gareth J., Lythgoe, David J., Kempton, Matthew J., McGuire, Philip, MacCabe, James H., Egerton, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891256/
https://www.ncbi.nlm.nih.gov/pubmed/35236831
http://dx.doi.org/10.1038/s41537-022-00230-2