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Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia
The neurobiological effects of clozapine are under characterised. We examined the effects clozapine treatment on subcortical volume and cortical thickness and investigated whether macrostructural changes were linked to alterations in glutamate or N-acetylaspartate (NAA). Data were acquired in 24 pat...
Autores principales: | Krajner, Fanni, Hadaya, Laila, McQueen, Grant, Sendt, Kyra-Verena, Gillespie, Amy, Avila, Alessia, Lally, John, Hedges, Emily P., Diederen, Kelly, Howes, Oliver D., Barker, Gareth J., Lythgoe, David J., Kempton, Matthew J., McGuire, Philip, MacCabe, James H., Egerton, Alice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891256/ https://www.ncbi.nlm.nih.gov/pubmed/35236831 http://dx.doi.org/10.1038/s41537-022-00230-2 |
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