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Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics

Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet, it is criticized for its lack of specificity, slow acquisition and processing times, and weak and noisy optical signals that lead to inaccuracies in quantification. We introduce FOCALS (Fast Optical Coherenc...

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Detalles Bibliográficos
Autores principales: Iyer, Rishyashring R., Sorrells, Janet E., Yang, Lingxiao, Chaney, Eric J., Spillman, Darold R., Tibble, Brian E., Renteria, Carlos A., Tu, Haohua, Žurauskas, Mantas, Marjanovic, Marina, Boppart, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891278/
https://www.ncbi.nlm.nih.gov/pubmed/35236862
http://dx.doi.org/10.1038/s41598-022-06926-w