Metformin suppresses the growth of colorectal cancer by targeting INHBA to inhibit TGF-β/PI3K/AKT signaling transduction

Multiple evidence shows that metformin serves as a potential agent for Colorectal Cancer (CRC) treatment, while its molecular mechanisms still require detailed investigation. Here, we revealed that metformin specifically suppressed the proliferation of CRC cells by causing G1/S arrest, and INHBA is...

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Detalles Bibliográficos
Autores principales: Xiao, Qing, Xiao, Jiani, Liu, Jiaqi, Liu, Jiaxin, Shu, Guang, Yin, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891354/
https://www.ncbi.nlm.nih.gov/pubmed/35236827
http://dx.doi.org/10.1038/s41419-022-04649-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891354/
https://www.ncbi.nlm.nih.gov/pubmed/35236827
http://dx.doi.org/10.1038/s41419-022-04649-4

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