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Integrated Chromatin Accessibility and Transcriptome Landscapes of 5-Fluorouracil-Resistant Colon Cancer Cells

Background: 5-Fluorouracil (5-FU) is one of the most effective and widely used chemotherapeutic drugs in the treatment of colon cancer, yet chemoresistance is a common feature of colon cancer treatment, resulting in poor prognosis and short survival. Dynamic reprogramming of chromatin accessibility...

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Detalles Bibliográficos
Autores principales: Zhang, Bishu, Lin, Jiewei, Zhang, Jiaqiang, Wang, Xuelong, Deng, Xiaxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891516/
https://www.ncbi.nlm.nih.gov/pubmed/35252200
http://dx.doi.org/10.3389/fcell.2022.838332