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TLR13 contributes to skeletal muscle atrophy by increasing insulin resistance in chronic kidney disease

OBJECTIVES: Insulin resistance in chronic kidney disease (CKD) stimulates muscle wasting, but the molecular processes behind the resistance are undetermined. However, inflammation in skeletal muscle is implicated in the pathogenesis of insulin resistance and cachexia. Toll‐like receptors (TLRs) are...

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Detalles Bibliográficos
Autores principales: Gu, Lijie, Wang, Zhifang, Zhang, Yueyue, Zhu, Nan, Li, Jiayong, Yang, Man, Wang, Ling, Rong, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891551/
https://www.ncbi.nlm.nih.gov/pubmed/35088922
http://dx.doi.org/10.1111/cpr.13181