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Piezo1 Participated in Decreased L-Type Calcium Current Induced by High Hydrostatic Pressure via. CaM/Src/Pitx2 Activation in Atrial Myocytes

Hypertension is a major cardiovascular risk factor for atrial fibrillation (AF) worldwide. However, the role of mechanical stress caused by hypertension on downregulating the L-type calcium current (I(Ca,L)), which is vital for AF occurrence, remains unclear. Therefore, the aim of the present study...

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Detalles Bibliográficos
Autores principales: Fang, Yuan, Li, Qian, Li, Xin, Luo, Guan-Hao, Kuang, Su-Juan, Luo, Xue-Shan, Li, Qiao-Qiao, Yang, Hui, Liu, Yang, Deng, Chun-Yu, Xue, Yu-Mei, Wu, Shu-Lin, Rao, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891577/
https://www.ncbi.nlm.nih.gov/pubmed/35252406
http://dx.doi.org/10.3389/fcvm.2022.842885