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DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model

Insulin resistance (IR) plays a critical role in cardiovascular diseases and metabolic diseases. In this study, we identified the downregulation of DMRT2 in adipose tissues from insulin-resistant subjects through bioinformatics analysis and in an insulin-resistant mouse model through experimental an...

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Detalles Bibliográficos
Autores principales: Tao, Jing, Yu, Xiao-Lin, Yuan, Yu-Juan, Shen, Xin, Liu, Jun, Gu, Pei-Pei, Wang, Zhao, Ma, Yi-Tong, Li, Guo-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891600/
https://www.ncbi.nlm.nih.gov/pubmed/35250844
http://dx.doi.org/10.3389/fendo.2021.723623