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Translocalization of enhanced PKM2 protein into the nucleus induced by cancer upregulated gene 2 confers cancer stem cell-like phenotypes

Increased mRNA levels of cancer upregulated gene (CUG)2 have been detected in many different tumor tissues using Affymetrix microarray. Oncogenic capability of the CUG2 gene has been further reported. However, the mechanism by which CUG2 overexpression promotes cancer stem cell (CSC)-like phenotypes...

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Detalles Bibliográficos
Autores principales: Yawut, Natpaphan, Kaowinn, Sirichat, Cho, Il-Rae, Budluang, Phatcharaporn, Kim, Seonghye, Kim, Suhkmann, Youn, So Eun, Koh, Sang Seok, Chung, Young-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891619/
https://www.ncbi.nlm.nih.gov/pubmed/35000669
http://dx.doi.org/10.5483/BMBRep.2022.55.2.118