Establishment of a Novel Mouse Hepatocellular Carcinoma Model for Dynamic Monitoring of Tumor Development by Bioluminescence Imaging

In this study, a novel mouse model of hepatocellular carcinoma (HCC) was established by simultaneously knocking out Pten and p53 suppressor genes and overexpressing c-Met and △90-β-catenin proto-oncogenes in the livers of mice via hydrodynamic injection (HDI). The mutations were introduced using the...

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Detalles Bibliográficos
Autores principales: Cao, Xiangyi, Zhang, Yulong, Zhou, Qianqian, Sun, Sujing, He, Minwei, Wang, Xiaohui, Ma, Ping, Yang, Xiaoang, Lv, Liping, Zhan, Linsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891637/
https://www.ncbi.nlm.nih.gov/pubmed/35251971
http://dx.doi.org/10.3389/fonc.2022.794101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891637/
https://www.ncbi.nlm.nih.gov/pubmed/35251971
http://dx.doi.org/10.3389/fonc.2022.794101

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