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AMP5A modulates Toll-like receptors 7 and 8 single-stranded RNA immune responses in PMA-differentiated THP-1 and PBMC

BACKGROUND: Dysregulation of antiviral immunity has been implicated in the progression of acute respiratory syndrome coronavirus 2 infection into severe cases of coronavirus disease of 2019 (COVID-19). Imbalances in the inflammatory response drive the overabundant production of pro-inflammatory cyto...

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Detalles Bibliográficos
Autores principales: Thomas, Gregory, Hirter, Kristen, Frederick, Elizabeth, Hausburg, Melissa, Bar-Or, Raphael, Mulugeta, Yetti, Roshon, Michael, Mains, Charles, Bar-Or, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891742/
https://www.ncbi.nlm.nih.gov/pubmed/35261923
http://dx.doi.org/10.1186/s41231-022-00110-y