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Withania somnifera Modulates Radiation-Induced Generation of Lung Cancer Stem Cells via Restraining the Hedgehog Signaling Factors

Cancer stem cells (CSCs) are implicated in the genesis, development, and recurrence of lung cancer (LC) with great resistance to radiation and chemotherapy. The aim of this study is to assess the inhibitory potential of ethanol extract of Withania somnifera (WS); 500 mg/kg body-weight/day and 8 Gy o...

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Detalles Bibliográficos
Autores principales: Moustafa, Enas Mahmoud, Abdel Salam, Hemat Sameeh, Mansour, Somaya Zakaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891860/
https://www.ncbi.nlm.nih.gov/pubmed/35250409
http://dx.doi.org/10.1177/15593258221076711