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The Potential Protective Effect of Curcumin and α-Lipoic Acid on N-(4-Hydroxyphenyl) Acetamide-induced Hepatotoxicity Through Downregulation of α-SMA and Collagen III Expression

BACKGROUND AND OBJECTIVES: N-(4-hydroxyphenyl) acetamide (NHPA) is the most commonly used analgesic and antipyretic agent worldwide; however, it remains the leading cause of drug-induced acute liver failure. This study explored the potential impact of curcumin (Curc) and/or α-lipoic acid (Lip acid)...

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Detalles Bibliográficos
Autores principales: Alhusain, Ahlam, Fadda, Laila, Sarawi, Wedad, Alomar, Hatun, Ali, Hanaa, Mahamad, Raeesa, Hasan, Iman, Badr, Amira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891863/
https://www.ncbi.nlm.nih.gov/pubmed/35250410
http://dx.doi.org/10.1177/15593258221078394