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HIF-1α Regulates Osteogenesis of Periosteum-Derived Stem Cells Under Hypoxia Conditions via Modulating POSTN Expression

Periosteum is indispensable in bone repair and is an important source of skeletal stem cells (SSCs) for endogenous bone regeneration. However, there are only a few studies about SSCs in periosteum. The craniomaxillofacial bone regeneration is done under the hypoxia microenvironment, in which HIF-1α...

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Detalles Bibliográficos
Autores principales: Zhuang, Yu, Zhao, Zhiyang, Cheng, Mengjia, Li, Meng, Si, Jiawen, Lin, Kaili, Yu, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891937/
https://www.ncbi.nlm.nih.gov/pubmed/35252198
http://dx.doi.org/10.3389/fcell.2022.836285