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Cortical porosity is elevated after a single dose of zoledronate in two rodent models of chronic kidney disease

PURPOSE: Patients with chronic kidney disease (CKD) have high risk of fracture in part due to cortical bone deterioration. The goal of this study was to assess the impact of two different bisphosphonates and dosing regimens on cortical microstructure (porosity, thickness, area) and bone mechanical p...

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Detalles Bibliográficos
Autores principales: Swallow, Elizabeth A., Metzger, Corinne E., Chen, Neal X., Wallace, Joseph M., Tippen, Samantha P., Kohler, Rachel, Moe, Sharon M., Allen, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891946/
https://www.ncbi.nlm.nih.gov/pubmed/35252482
http://dx.doi.org/10.1016/j.bonr.2022.101174