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The leucine-rich repeat domains of BK channel auxiliary γ subunits regulate their expression, trafficking, and channel-modulation functions

As high-conductance calcium- and voltage-dependent potassium channels, BK channels consist of pore-forming, voltage-, and Ca(2+)-sensing α and auxiliary subunits. The leucine-rich repeat (LRR) domain–containing auxiliary γ subunits potently modulate the voltage dependence of BK channel activation. D...

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Detalles Bibliográficos
Autores principales: Chen, Guanxing, Li, Qin, Yan, Jiusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892010/
https://www.ncbi.nlm.nih.gov/pubmed/35104503
http://dx.doi.org/10.1016/j.jbc.2022.101664