Cargando…
The leucine-rich repeat domains of BK channel auxiliary γ subunits regulate their expression, trafficking, and channel-modulation functions
As high-conductance calcium- and voltage-dependent potassium channels, BK channels consist of pore-forming, voltage-, and Ca(2+)-sensing α and auxiliary subunits. The leucine-rich repeat (LRR) domain–containing auxiliary γ subunits potently modulate the voltage dependence of BK channel activation. D...
Autores principales: | Chen, Guanxing, Li, Qin, Yan, Jiusheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892010/ https://www.ncbi.nlm.nih.gov/pubmed/35104503 http://dx.doi.org/10.1016/j.jbc.2022.101664 |
Ejemplares similares
-
Regulation of BK channels by auxiliary γ subunits
por: Zhang, Jiyuan, et al.
Publicado: (2014) -
BK channel modulation by positively charged peptides and auxiliary γ subunits mediated by the Ca(2+)-bowl site
por: Chen, Guanxing, et al.
Publicado: (2023) -
Relationship between auxiliary gamma subunits and mallotoxin on BK channel modulation
por: Guan, Xin, et al.
Publicado: (2017) -
Molecular basis for differential modulation of BK channel voltage-dependent gating by auxiliary γ subunits
por: Li, Qin, et al.
Publicado: (2015) -
The single transmembrane segment determines the modulatory function of the BK channel auxiliary γ subunit
por: Li, Qin, et al.
Publicado: (2016)