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Agonist-induced phosphorylation of orthologues of the orphan receptor GPR35 functions as an activation sensor

G protein-coupled receptor 35 (GPR35) is poorly characterized but nevertheless has been revealed to have diverse roles in areas including lower gut inflammation and pain. The development of novel reagents and tools will greatly enhance analysis of GPR35 functions in health and disease. Here, we used...

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Detalles Bibliográficos
Autores principales: Divorty, Nina, Jenkins, Laura, Ganguly, Amlan, Butcher, Adrian J., Hudson, Brian D., Schulz, Stefan, Tobin, Andrew B., Nicklin, Stuart A., Milligan, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892012/
https://www.ncbi.nlm.nih.gov/pubmed/35101446
http://dx.doi.org/10.1016/j.jbc.2022.101655