FNDC5/irisin facilitates muscle−adipose−bone connectivity through ubiquitination-dependent activation of runt-related transcriptional factors RUNX1/2

In the past decade, the cleavage protein irisin derived from fibronectin type III domain–containing protein 5 (FNDC5) in exercise-stimulated skeletal muscle has increasingly become a biomarker associated with metabolic syndrome and osteoporosis in humans. However, it is unclear how this protein faci...

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Detalles Bibliográficos
Autores principales: He, Xinyu, Hua, Yue, Li, Qian, Zhu, Wei, Pan, Yu, Yang, Yilin, Li, Xinyang, Wu, Mengxiao, Wang, Jiyong, Gan, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892030/
https://www.ncbi.nlm.nih.gov/pubmed/35124008
http://dx.doi.org/10.1016/j.jbc.2022.101679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892030/
https://www.ncbi.nlm.nih.gov/pubmed/35124008
http://dx.doi.org/10.1016/j.jbc.2022.101679

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