Endosomal TLR3 signaling in stromal osteoblasts induces prostaglandin E(2)–mediated inflammatory periodontal bone resorption

Toll-like receptors (TLRs) are pattern recognition receptors that play a critical role in innate immune diseases. TLR3, which is localized in the endosomal compartments of hematopoietic immune cells, is able to recognize double-stranded RNA (dsRNA) derived from viruses and bacteria and thereby induc...

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Detalles Bibliográficos
Autores principales: Tominari, Tsukasa, Akita, Miyuki, Matsumoto, Chiho, Hirata, Michiko, Yoshinouchi, Shosei, Tanaka, Yuki, Karouji, Kento, Itoh, Yoshifumi, Maruyama, Takayuki, Miyaura, Chisato, Numabe, Yukihiro, Inada, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892075/
https://www.ncbi.nlm.nih.gov/pubmed/35101442
http://dx.doi.org/10.1016/j.jbc.2022.101603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892075/
https://www.ncbi.nlm.nih.gov/pubmed/35101442
http://dx.doi.org/10.1016/j.jbc.2022.101603

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