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Metabolic regulation of ferroptosis in the tumor microenvironment

Ferroptosis is an iron-dependent, nonapoptotic form of regulated cell death triggered by impaired redox and antioxidant machinery and propagated by the accumulation of toxic lipid peroxides. A compendium of experimental studies suggests that ferroptosis is tumor-suppressive. Sensitivity or resistanc...

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Detalles Bibliográficos
Autores principales: Mbah, Nneka E., Lyssiotis, Costas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892088/
https://www.ncbi.nlm.nih.gov/pubmed/35065965
http://dx.doi.org/10.1016/j.jbc.2022.101617