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Metabolic regulation of ferroptosis in the tumor microenvironment
Ferroptosis is an iron-dependent, nonapoptotic form of regulated cell death triggered by impaired redox and antioxidant machinery and propagated by the accumulation of toxic lipid peroxides. A compendium of experimental studies suggests that ferroptosis is tumor-suppressive. Sensitivity or resistanc...
Autores principales: | Mbah, Nneka E., Lyssiotis, Costas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892088/ https://www.ncbi.nlm.nih.gov/pubmed/35065965 http://dx.doi.org/10.1016/j.jbc.2022.101617 |
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