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Oxidized alkyl phospholipids stimulate sodium transport in proximal tubules via a nongenomic PPARγ-dependent pathway

Oxidized phospholipids have been shown to exhibit pleiotropic effects in numerous biological contexts. For example, 1-O-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (azPC), an oxidized phospholipid formed from alkyl phosphatidylcholines, is a peroxisome proliferator–activated receptor gamma (PPA...

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Detalles Bibliográficos
Autores principales: Mizuno, Tomohito, Satoh, Nobuhiko, Horita, Shoko, Tsukada, Hiroyuki, Takagi, Mayuko, Sato, Yusuke, Kume, Haruki, Nangaku, Masaomi, Nakamura, Motonobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892145/
https://www.ncbi.nlm.nih.gov/pubmed/35124009
http://dx.doi.org/10.1016/j.jbc.2022.101681