Recreating the natural evolutionary trend in key microdomains provides an effective strategy for engineering of a thermomicrobial N-demethylase

N-demethylases have been reported to remove the methyl groups on primary or secondary amines, which could further affect the properties and functions of biomacromolecules or chemical compounds; however, the substrate scope and the robustness of N-demethylases have not been systematically investigate...

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Detalles Bibliográficos
Autores principales: Xin, Yu, Shen, Chen, Tang, Mengwei, Guo, Zitao, Shi, Yi, Gu, Zhenghua, Shao, Jun, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892156/
https://www.ncbi.nlm.nih.gov/pubmed/35124004
http://dx.doi.org/10.1016/j.jbc.2022.101656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892156/
https://www.ncbi.nlm.nih.gov/pubmed/35124004
http://dx.doi.org/10.1016/j.jbc.2022.101656

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