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LPGAT1 controls the stearate/palmitate ratio of phosphatidylethanolamine and phosphatidylcholine in sn-1 specific remodeling

Most mammalian phospholipids contain a saturated fatty acid at the sn-1 carbon atom and an unsaturated fatty acid at the sn-2 carbon atom of the glycerol backbone group. While the sn-2 linked chains undergo extensive remodeling by deacylation and reacylation (Lands cycle), it is not known how the co...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Miller, Paighton C., Phoon, Colin K.L., Ren, Mindong, Nargis, Titli, Rajan, Sujith, Hussain, M. Mahmood, Schlame, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892159/
https://www.ncbi.nlm.nih.gov/pubmed/35131264
http://dx.doi.org/10.1016/j.jbc.2022.101685