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Dacarbazine-Loaded Targeted Polymeric Nanoparticles for Enhancing Malignant Melanoma Therapy

Dacarbazine (DTIC) dominates chemotherapy for malignant melanoma (MM). However, the hydrophobicity, photosensitivity, instability, and toxicity to normal cells of DTIC limit its efficacy in treating MM. In the present study, we constructed star-shaped block polymers nanoparticles (NPs) based on Chol...

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Detalles Bibliográficos
Autores principales: Xiong, Wei, Guo, Zhengdong, Zeng, Baoyan, Wang, Teng, Zeng, Xiaowei, Cao, Wei, Lian, Daizheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892180/
https://www.ncbi.nlm.nih.gov/pubmed/35252156
http://dx.doi.org/10.3389/fbioe.2022.847901