An RRx-001 Analogue With Potent Anti-NLRP3 Inflammasome Activity but Without High-Energy Nitro Functional Groups

NLRP3 inflammasome is involved in the pathology of multiple human inflammatory diseases but there are still no clinically available medications targeting the NLRP3 inflammasome. We have previously identified RRx-001 as a highly selective and potent NLRP3 inhibitor, however, it contains high-energy n...

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Detalles Bibliográficos
Autores principales: Lin, Hualong, Yang, Mingyang, Li, Cong, Lin, Bolong, Deng, Xianming, He, Hongbin, Zhou, Rongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892206/
https://www.ncbi.nlm.nih.gov/pubmed/35250572
http://dx.doi.org/10.3389/fphar.2022.822833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892206/
https://www.ncbi.nlm.nih.gov/pubmed/35250572
http://dx.doi.org/10.3389/fphar.2022.822833

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