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Myosin VI regulates ciliogenesis by promoting the turnover of the centrosomal/satellite protein OFD1

The actin motor protein myosin VI is a multivalent protein with diverse functions. Here, we identified and characterised a myosin VI ubiquitous interactor, the oral‐facial‐digital syndrome 1 (OFD1) protein, whose mutations cause malformations of the face, oral cavity, digits and polycystic kidney di...

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Detalles Bibliográficos
Autores principales: Magistrati, Elisa, Maestrini, Giorgia, Niño, Carlos A, Lince‐Faria, Mariana, Beznoussenko, Galina, Mironov, Alexandre, Maspero, Elena, Bettencourt‐Dias, Mónica, Polo, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892233/
https://www.ncbi.nlm.nih.gov/pubmed/34957672
http://dx.doi.org/10.15252/embr.202154160