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The Role of HMGB1 in Rheumatic Diseases

HMGB1, a highly conserved non-histone nuclear protein, is widely expressed in mammalian cells. HMGB1 in the nucleus binds to the deoxyribonucleic acid (DNA) to regulate the structure of chromosomes and maintain the transcription, replication, DNA repair, and nucleosome assembly. HMGB1 is actively or...

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Detalles Bibliográficos
Autores principales: Dong, Yuanji, Ming, Bingxia, Dong, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892237/
https://www.ncbi.nlm.nih.gov/pubmed/35250993
http://dx.doi.org/10.3389/fimmu.2022.815257